La transformación de la práctica cardiológica por la inteligencia artificial: Desde el cribado clínico hasta la toma de decisiones personalizadas

Autores/as

DOI:

https://doi.org/10.5281/zenodo.17887328

Palabras clave:

Inteligencia Artificial, Cardiología, Aprendizaje Automático (Machine Learning), Medicina de Precisión, Sesgo Algorítmico, Sistemas de Apoyo a la Decisión Clínica

Resumen

Introducción: La práctica cardiológica contemporánea enfrenta limitaciones humanas inherentes, como la variabilidad interobservador y la inercia terapéutica, en un contexto de creciente demanda asistencial. La inteligencia artificial (IA) emerge como un paradigma disruptivo capaz de redefinir el continuo de atención, desde el cribado hasta la medicina de precisión. Esta revisión integrativa analiza el impacto clínico, pronóstico y ético de la IA en la cardiología moderna.

Métodos: Se realizó una revisión integrativa siguiendo el marco de Whittemore y Knafl. Se llevó a cabo una búsqueda sistemática en PubMed, Scopus y Google Scholar de estudios publicados entre 2019 y 2025. Se incluyeron investigaciones originales y revisiones sistemáticas sobre aprendizaje automático (Machine Learning) y aprendizaje profundo (Deep Learning) aplicados al diagnóstico, pronóstico y tratamiento cardiovascular.

Resultados: La síntesis de la evidencia revela que los algoritmos de IA en dispositivos ponibles (wearables) alcanzan una sensibilidad del 99.6 % para la detección de fibrilación auricular, facilitando el cribado masivo. En el ámbito pronóstico, los modelos de aprendizaje automático superan a los scores tradicionales (Framingham/SCORE), elevando el índice-C de 0.61 a 0.68 en la predicción de eventos adversos mayores (MACE). Asimismo, la automatización en imagenología (RMN/TC) y el fenotipado digital optimizan la precisión diagnóstica y la personalización terapéutica. Sin embargo, persisten barreras críticas para la implementación, destacando la opacidad de los algoritmos tipo «caja negra» y el riesgo de sesgos algorítmicos en poblaciones subrepresentadas, lo que amenaza la equidad en salud.

Conclusiones: La IA no reemplaza al cardiólogo, sino que instaura una era de «inteligencia aumentada» que potencia la precisión diagnóstica y la estratificación del riesgo. La transición hacia la práctica clínica rutinaria requiere superar desafíos de explicabilidad, validar modelos en poblaciones diversas para mitigar sesgos y garantizar la interoperabilidad de los sistemas.

Referencias

Ahmed MM, Okesanya OJ, Olaleke NO, Adigun OA, Adebayo UO, Oso TA, et al. Integrating digital health innovations to achieve universal health coverage: Promoting health outcomes and quality through global public health equity. Healthcare (Basel). 2025;13(9):1060. doi: 10.3390/healthcare13091060

Song J, Wang X, Wang B, Gao Y, Liu J, Zhang H, et al. Effectiveness of a clinical decision support system for hypertension management in primary care: study protocol for a pragmatic cluster-randomized controlled trial. Trials. 2022;23(1):412. doi: 10.1186/s13063-022-06374-x

Antoun I, Abdelrazik A, Eldesouky M, Li X, Layton GR, Zakkar M, et al. Artificial intelligence in atrial fibrillation: emerging applications, research directions and ethical considerations. Front Cardiovasc Med. 2025;12:1596574. doi: 10.3389/fcvm.2025.1596574

Kolossváry M, Sereti I, Zanni MV, Fichtenbaum CJ, Aberg JA, Bloomfield GS, et al. Statin-dependent and -independent pathways are associated with major adverse cardiovascular events in people with HIV. J Clin Invest. 2025;135(22). doi: 10.1172/jci196021

Tamarappoo BK, Lin A, Commandeur F, McElhinney PA, Cadet S, Goeller M, et al. Machine learning integration of circulating and imaging biomarkers for explainable patientspecific prediction of cardiac events: A prospective study. Atherosclerosis. 2021;318:76–82. doi: 10.1016/j.atherosclerosis.2020.11.008

Santala OE, Lipponen JA, Jäntti H, Rissanen TT, Tarvainen MP, Laitinen TP, et al. Continuous mHealth patch monitoring for the algorithm-based detection of atrial fibrillation: Feasibility and diagnostic accuracy study. JMIR Cardio. 2022;6(1):e31230. doi: 10.2196/31230

Böttcher B, Beller E, Busse A, Cantré D, Yücel S, Öner A, et al. Fully automated quantification of left ventricular volumes and function in cardiac MRI: clinical evaluation of a deep learning-based algorithm. Int J Cardiovasc Imaging. 2020;36(11):2239–47. doi: 10.1007/s10554-020-01935-0

Gautam A, Raghav P, Subramaniam V, Kumar S, Kumar S, Jain D, et al. Fully automated Agatston score calculation from electrocardiography-gated cardiac computed tomography using deep learning and multi-organ segmentation: A validation study. Angiology. 2025;76(5):431–40. doi: 10.1177/00033197231225286

Hicks SA, Isaksen JL, Thambawita V, Ghouse J, Ahlberg G, Linneberg A, et al. Explaining deep neural networks for knowledge discovery in electrocardiogram analysis. Sci Rep. 2021;11(1):10949. doi: 10.1038/s41598-021-90285-5

Zeineldin RA, Karar ME, Elshaer Z, Coburger J, Wirtz CR, Burgert O, et al. Explainable hybrid vision transformers and convolutional network for multimodal glioma segmentation in brain MRI. Sci Rep. 2024;14(1):3713. doi: 10.1038/s41598-024-54186-7

Puyol-Antón E, Ruijsink B, Mariscal Harana J, Piechnik SK, Neubauer S, Petersen SE, et al. Fairness in cardiac magnetic resonance imaging: Assessing sex and racial bias in deep learning-based segmentation. Front Cardiovasc Med. 2022;9(859310):859310. doi: 10.3389/fcvm.2022.859310

Vardas EP, Marketou M, Vardas PE. Medicine, healthcare and the AI act: gaps, challenges and future implications. Eur Heart J Digit Health. 2025;6(4):833–9. doi: 10.1093/ehjdh/ztaf041

Chen E, Jiang J, Su R, Gao M, Zhu S, Zhou J, et al. A new smart wristband equipped with an artificial intelligence algorithm to detect atrial fibrillation. Heart Rhythm. 2020;17(5 Pt B):847–53. doi: 10.1016/j.hrthm.2020.01.034

Baek YS, Kwon S, You SC, Lee KN, Yu HT, Lee SR, et al. Artificial intelligence-enhanced 12-lead electrocardiography for identifying atrial fibrillation during sinus rhythm (AIAFib) trial: protocol for a multicenter retrospective study. Front Cardiovasc Med. 2023;10:1258167. doi: 10.3389/fcvm.2023.1258167

Khalifa A, Abdulaziz M, Parvez SS, Salem A, Panhwer HS, Saleem U, et al. The digital revolution in cardiac ischemia: Artificial intelligence (AI)-enhanced detection, diagnosis, and risk stratification. Cureus. 2025;17(10):e95059. doi: 10.7759/cureus.95059

Giebel GD, Gissel C. Accuracy of mHealth devices for atrial fibrillation screening: Systematic Review. JMIR MHealth UHealth. 2019;7(6):e13641. doi: 10.2196/13641

Hartikainen S, Lipponen JA, Hiltunen P, Rissanen TT, Kolk I, Tarvainen MP, et al. Effectiveness of the chest strap electrocardiogram to detect atrial fibrillation. Am J Cardiol. 2019;123(10):1643–8. doi: 10.1016/j.amjcard.2019.02.028

Duffy G, Cheng PP, Yuan N, He B, Kwan AC, Shun-Shin MJ, et al. High-throughput precision phenotyping of left ventricular hypertrophy with cardiovascular deep learning. JAMA Cardiol. 2022;7(4):386–95. doi: 10.1001/jamacardio.2021.6059

Maturi B, Dulal S, Sayana SB, Ibrahim A, Ramakrishna M, Chinta V, et al. Revolutionizing cardiology: The role of artificial intelligence in echocardiography. J Clin Med. 2025;14(2):625. doi: 10.3390/jcm14020625

Ghorbani A, Ouyang D, Abid A, He B, Chen JH, Harrington RA, et al. Deep learning interpretation of echocardiograms. NPJ Digit Med. 2020;3(1):10. doi: 10.1038/s41746-019-0216-8

Wang J, Zhang N, Wang S, Liang W, Zhao H, Xia W, et al. AI approach to biventricular function assessment in cine-MRI: an ultra-small training dataset and multivendor study. Phys Med Biol. 2023;68(24):245025. doi: 10.1088/1361-6560/ad0903

Gautam A, Raghav P, Subramanya V, Kumar S, Kumar S, Jain D, et al. Fully Automated Agatston score calculation from ECG gated Cardiac CT using Deep learning and Multiorgan Segmentation: A Validation study. Research Square. 2022. doi: 10.21203/rs.3.rs-2347144/v1

Tian D, Yu N, Mao T, Li Y, Liu R, Xu Y, et al. Prediction of long-term major adverse cardiac events after myocardial infarction: value of combination of inflammatory biomarkers and GRACE score. Front Cardiovasc Med. 2025;12(1591578):1591578. doi: 10.3389/fcvm.2025.1591578

Shinohara H, Kodera S, Nagae Y, Hiruma T, Kobayashi A, Sato M, et al. The potential of the transformer-based survival analysis model, SurvTrace, for predicting recurrent cardiovascular events and stratifying high-risk patients with ischemic heart disease. PLoS One. 2024;19(6):e0304423. doi: 10.1371/journal.pone.0304423

Moltó-Balado P, Reverté-Villarroya S, Alonso-Barberán V, Monclús-Arasa C, Balado-Albiol MT, Clua-Queralt J, et al. Machine learning approaches to predict Major Adverse Cardiovascular Events in atrial fibrillation. Technologies (Basel). 2024;12(2):13. doi: 10.3390/technologies12020013

Oo MM, Gao C, Cole C, Hummel Y, Guignard-Duff M, Jefferson E, et al. Artificial intelligenceassisted automated heart failure detection and classification from electronic health records. ESC Heart Fail. 2024;11(5):2769–77. doi: 10.1002/ehf2.14828

Shao Y, Zhang S, Raman VK, Patel SS, Cheng Y, Parulkar A, et al. Artificial intelligence approaches for phenotyping heart failure in U.S. Veterans Health Administration electronic health record. ESC Heart Fail. 2024;11(5):3155–66. doi: 10.1002/ehf2.14787

Mortazavi BJ, Downing NS, Bucholz EM, Dharmarajan K, Manhapra A, Li SX, et al. Analysis of machine learning techniques for heart failure readmissions. Circ Cardiovasc Qual Outcomes. 2016;9(6):629–40. doi: 10.1161/circoutcomes.116.003039

Banerjee A, Chen S, Fatemifar G, Zeina M, Lumbers RT, Mielke J, et al. Machine learning for subtype definition and risk prediction in heart failure, acute coronary syndromes and atrial fibrillation: systematic review of validity and clinical utility. BMC Med. 2021;19(1):85. doi: 10.1186/s12916-02101940-7

Weller J, Gutton J, Hocquet G, Pellet L, Aroulanda MJ, Bruandet A, et al. Prediction of 90 day mortality in elderly patients with acute HF from e-health records using artificial intelligence. ESC Heart Fail. 2025;12(3):2200–9. doi: 10.1002/ehf2.15244

Kwon JM, Kim KH, Jeon KH, Lee SE, Lee HY, Cho HJ, et al. Artificial intelligence algorithm for predicting mortality of patients with acute heart failure. PLoS One. 2019;14(7):e0219302. doi: 10.1371/journal.pone.0219302

Kasem Ali Sliman R, Eitan A, Zisman K, Avidan Y, Aker A, Sliman H. Three-cusp view orientation in TAVI: Evaluating LOA versus non-LOA impact on outcomes with contemporary valve prostheses. Catheter Cardiovasc Interv. 2025;106(4):2567–78. doi: 10.1002/ccd.70087

Butter C, Kaneko H, Tambor G, Hara M, Neuss M, Hoelschermann F. Clinical utility of intraprocedural three-dimensional integrated image guided transcatheter aortic valve implantation using novel automated computed tomography software: A single-center preliminary experience. Catheter Cardiovasc Interv. 2019;93(4):722–8. doi: 10.1002/ccd.27920

Felbel D, Buck C, Riedel N, Paukovitsch M, Stephan T, Krohn-Grimberghe M, et al. Combined computed coronary tomography angiography and transcatheter aortic valve implantation (TAVI) planning computed tomography reliably detects relevant coronary artery disease pre-TAVI. J Clin Med. 2024;13(16):4885. doi: 10.3390/jcm13164885

Panuccio G, Abdelwahed YS, Carabetta N, Salerno N, Leistner DM, Landmesser U, et al. Clinical and procedural outcomes of IVUS-guided vs. Angiography-guided CTO-PCI: A systematic review and meta-analysis. J Clin Med. 2023;12(15):4947. doi: 10.3390/jcm12154947

Hoque A, Ahmed I, Nahar N, Saria SJ, Islam S, MD Mehedi Hasan, et al. Ai-assisted imaging and navigation in Minimally invasive cardiac interventions - a systematic review. Insights-Journal of Health and Rehabilitation. 2025;3(2):538–44. doi: 10.71000/ky41as49

Hopkisson O, Ibrahem A, Swinn T, Dastidar A, Satti Z. Contemporary review of cardiovascular computed tomography in coronary and structural heart interventions. Preprints. 2025. doi: 10.20944/preprints202502.1726.v1

Ashiq K, Ashiq S, Mustafa N. Pharmacogenomics and the concept of personalized medicine for the management of hypertension. Pak Hear J. 2023;56(2):188–90. doi: 10.47144/phj.v56i2.2553

Afrose N, Chakraborty R, Hazra A, Bhowmick P, Bhowmick M. AI-driven drug discovery and development. In: Future of AI in Biomedicine and Biotechnology. IGI Global; 2024. p. 259–77. doi: 10.4018/979-8-3693-3629-8.ch013

Iftikhar H. AI-driven pharmacovigilance and molecular profiling of fluoroquinolone-associated cardiotoxicity in the UAE: A geospatial and machine learning analysis with structural modification strategies (2018-2023). medRxiv. 2025. doi: 10.1101/2025.05.10.25327319

Szymańska K, Szmyt K, Krasnoborska J, Samojedny S, Superson M, Walczak K, et al. Revolutionizing cardiovascular treatments with the use of AI: Current status and future prospects. Qual Sport. 2024;19:53072. doi: 10.12775/qs.2024.19.53072

Chandan TR, Patil CD, Kundgir VB, Chaudhari K, Bachhav RL, Bhamare MS, et al. Pharmacogenomics and personalized medicine: A revolution in drug therapy. Res J Pharmacol Pharmacodyn. 2025;311–8. doi: 10.52711/2321-5836.2025.00048

Kawamoto K, Houlihan CA, Balas EA, Lobach DF. Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success. BMJ. 2005;330(7494):765. doi: 10.1136/bmj.38398.500764.8f

Cai J, Li P, Li W, Zhu T. Outcomes of clinical decision support systems in real-world perioperative care: a systematic review and meta-analysis. Int J Surg. 2024;110(12):8057–72. doi: 10.1097/js9.0000000000001821

Bozyel S, Şimşek E, Koçyiğit Burunkaya D, Güler A, Korkmaz Y, Şeker M, et al. Artificial intelligence-based clinical decision support systems in cardiovascular diseases. Anatol J Cardiol. 2024;74–86. doi: 10.14744/anatoljcardiol.2023.3685

Giuste F, Shi W, Zhu Y, Naren T, Isgut M, Sha Y, et al. Explainable Artificial Intelligence methods in combating pandemics: A systematic review. IEEE Rev Biomed Eng. 2023;16:5–21. doi: 10.1109/rbme.2022.3185953

Linardatos P, Papastefanopoulos V, Kotsiantis S. Explainable AI: A review of machine learning interpretability methods. Entropy (Basel). 2020;23(1):18. doi: 10.3390/e23010018

Aasem M, Javed Iqbal M. Toward explainable AI in radiology: Ensemble-CAM for effective thoracic disease localization in chest X-ray images using weak supervised learning. Front Big Data. 2024;7:1366415. doi: 10.3389/fdata.2024.1366415

Petch J, Di S, Nelson W. Opening the black box: The promise and limitations of explainable machine learning in cardiology. Can J Cardiol. 2022;38(2):204–13. doi: 10.1016/j.cjca.2021.09.004

Jones RK. Algorithmic bias and fairness in biomedical and health research. In: Advances in Computational Intelligence and Robotics. IGI Global Scientific Publishing; 2025. p. 287–324. doi: 10.4018/9798-3373-4252-8.ch008

Oyeniran OC, Adewusi AO, Adeleke AG, Akwawa LA, Azubuko CF. Ethical AI: Addressing bias in machine learning models and software applications. Comput sci IT res j. 2022;3(3):115–26. doi: 10.51594/csitrj.v3i3.1559

Bhimavarapu U. Bias in AI-driven diabetes prediction models: Challenges, impacts, and mitigation strategies. In: Advances in Computational Intelligence and Robotics. IGI Global; 2025. p. 195–214. doi: 10.4018/979-8-3693-9735-0.ch008

Saleiro P, Kuester B, Hinkson L, London J, Stevens A, Anisfeld A, et al. Aequitas: A bias and fairness audit toolkit. arXiv. 2018. doi: 10.48550/arxiv.1811.05577

Dakshit S, Dakshit S, Khargonkar N, Prabhakaran B. Bias analysis in healthcare time series (BAHT) decision support systems from meta data. J Healthc Inform Res. 2023;7(2):225–53. doi: 10.1007/s41666023-00133-6

Al-Nafjan A, Aljuhani A, Alshebel A, Alharbi A, Alshehri A. Artificial intelligence in predictive healthcare: A systematic review. J Clin Med. 2025;14(19):6752. doi: 10.3390/jcm14196752

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2026-07-25

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La transformación de la práctica cardiológica por la inteligencia artificial: Desde el cribado clínico hasta la toma de decisiones personalizadas. (2026). Revista UniNorte De Medicina Y Ciencias De La Salud, 14(2), 53–62. https://doi.org/10.5281/zenodo.17887328

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