Injuria renal aguda en unidad de cuidados intensivos

Autores/as

  • Igor Ernesto Marcet-Franco Universidad del Norte, Paraguay Autor/a
  • Darío Ramón Cuevas Benítez Instituto de Previsión Social, Paraguay Autor/a
  • Elvira Giménez Rolón Instituto de Previsión Social, Paraguay Autor/a
  • Maria del Carmen Romero Instituto de Previsión Social, Paraguay Autor/a
  • Amalia Beatriz Molinas de López Instituto de Previsión Social, Paraguay Autor/a
  • Roger Aureliano Ayala Ferrari Instituto de Previsión Social, Paraguay Autor/a
  • Juan Daniel Acosta González Instituto de Previsión Social, Paraguay Autor/a
  • María Belén Giménez-Reyes Universidad del Norte, Paraguay Autor/a

DOI:

https://doi.org/10.5281/zenodo.6884912

Palabras clave:

ciencias de la salud

Resumen

Objetivos: 1) Describir el tipo de población afecta a injuria renal aguda (IRA) en el contexto de una hospitalización en unidad de cuidados intensivos; 2) determinar la etiología de la IRA en la población de estudio, describir los tipos de tratamientos recibidos tanto médicos como de terapias de reemplazo renal; 3) cuantificar la mortalidad intrahospitalaria y el grado de recuperación de la función renal en la población superviviente

Material y método: Este fue un trabajo observacional prospectivo conducido en un hospital universitario de tercer nivel, desde el 1 de enero al 31 de diciembre de 2018. En este lapso se reclutaron 142 pacientes con una creatininemia superior a 2 mg/dl o aumento del 50% sobre sus valores basales

Resultados: En muestra serie se notamos una preponderancia masculina (63%), con comorbilidades (89%). Entre ellas, la diabetes e hipertensión arterial fueron las más frecuentes (76%). Encontramos un contingente considerable de IRA prerrenal (61%) que luego evolucionaría a formas más graves relacionadas con sepsis y choque séptico (68%). Los puntajes de gravedad al ingreso y evolutivos se correlacionaron con una mortalidad elevada (77%). No pudimos descartar el papel de los diuréticos en la mala evolución

Descargas

Los datos de descarga aún no están disponibles.

Referencias

Amdur, R. L., Chawla, L. S., Amodeo, S., Kimmel, P. L., & Palant, C. E. (2009). Outcomes following diagnosis of acute renal failure in U.S. veterans: Focus on acute tubular necrosis. Kidney International, 76(10), 1089-1097

Bagshaw, S. M., George, C., Bellomo, R., & ANZICS Database Management Committe. (2008). A COMPARISON of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 23(5), 1569-1574

Bagshaw, S. M., George, C., Dinu, I., & Bellomo, R. (2008). A multi-centre evaluation of the RIFLE criteria for early acute kidney injury in critically ill patients. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 23(4), 1203-1210

Bellomo, R., Kellum, J. A., & Ronco, C. (2012). Acute kidney injury. Lancet, 380(9843), 756-766

Bellomo, R., Ronco, C., Kellum, J. A., Mehta, R. L., Palevsky, P., & Acute Dialysis Quality Initiative workgroup. (2004). Acute renal failure - Definition, outcome measures, animal models, fluid therapy and information technology needs: The Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Critical Care, 8(4), R204-212

Brivet, F. G., Kleinknecht, D. J., Loirat, P., & Landais, P. J. (1996). Acute renal failure in intensive care units— Causes, outcome, and prognostic factors of hospital mortality: A prospective, multicenter study. French Study Group on Acute Renal Failure. Critical Care Medicine, 24(2), 192-198

Chew, S. L., Lins, R. L., Daelemans, R., & De Broe, M. E. (1993). Outcome in acute renal failure. Nephrology, Dialysis, Transplantation, 8(2), 101-107

Demirjian, S., Chertow, G. M., Zhang, J. H., O’Connor, T. Z., Vitale, J., Paganini, E. P., Palevsky, P. M., & VA/NIH Acute Renal Failure Trial Network. (2011). Model to predict mortality in critically ill adults with acute kidney injury. Clinical Journal of the American Society of Nephrology, 6(9), 2114-2120

Holley, J. L. (2009). Clinical approach to the diagnosis of acute renal failure. En A. Greenberg & A. K. Cheung (Eds.), Primer on kidney diseases (5th ed). Saunders/Elsevier: National Kidne y Foundation

Kaufman, J., Dhakal, M., Patel, B., & Hamburger, R. (1991). Community- acquired acute renal failure. American Journal of Kidney Diseases, 17(2), 191- 198

Kellum, J. A., Sileanu, F. E., Murugan, R., Lucko, N., Shaw, A. D., & Clermont, G. (2015). Classifying AKI by urine output versus serum creatinine level. Journal of the American Society of Nephrology, 26(9), 2231-2238

Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985). APACHE II: A severity of disease classification system. Critical Care Medicine, 13(10), 818-829

Leite, T. T., Macedo, E., Pereira, S. M., Bandeira, S. R. C., Pontes, P. H. S., Garcia, A. S., Milit ão, F. R., Sobrinho, I. M. M., Assunção, L. M., & Libório, A. B. (2013). Timing of renal replacement therapy initiation by AKIN classification system. Critical Care, 17(2), R62

Liaño, F., & Pascual, J. (1996). Epidemiology of acute renal failure: A prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group. Kidney International, 50(3), 811-818

Liu, W.-L., Wang, J.-Y., Huang, T.-M., Lai, C.-C., Wang, C.-Y., Yeh, Y.-C., Chou, A., Chu, T.-S., Lin, Y.-F., Chiu, J.-S., Tsai, P.-R., Wu, V.-C., Ko, W.-J., Wu, K.-D., &

Wang, W.-J. (2012). Hospital mortality of septic acute kidney injury requiring renal replacement therapy in the postoperative elderly. International Journal of Gerontology, 6(2), 75-79

Mataloun, S. E., Machado, F. R., Senna, A. P. R., Guimarães, H. P., & Amaral, J. L. G. (2006). Incidence, risk factors and prognostic factors of acute renal failure in patients admitted to an intensive care unit. Brazilian Journal of Medical and Biological Research, 39(10), 1339-1347

Mehta, R. L., & Chertow, G. M. (2003). Acute renal failure definitions and classification: Time for change? Journal of the American Society of Nephrology, 14(8), 2178-2187

Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B. A., Ronco, C., Warnock, D. G., Levin, A., & Acute Kidney Injury Network. (2007). Acute Kidney Injury Network: Report of an initiative to improve outcomes in acute kidney injury. Critical Care, 11(2), R31

Mehta, R. L., Pascual, M. T., Soroko, S., Chertow, G. M., & PICARD Study Group. (2002). Diuretics, mortality, and nonrecovery of renal function in acute renal failure. JAMA, 288(20), 2547-2553

Metnitz, P. G. H., Krenn, C. G., Steltzer, H., Lang, T., Ploder, J., Lenz, K., Le Gall, J.-R., & Druml, W. (2002). Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients. Critical Care Medicine, 30(9), 2051-2058

Nash, K., Hafeez, A., & Hou, S. (2002). Hospital-acquired renal insufficiency. American Journal of Kidney Diseases, 39(5), 930-936

Oppert, M., Engel, C., Brunkhorst, F.-M., Bogatsch, H., Reinhart, K., Frei, U., Eckardt, K.-U., Loeffler, M., John, S., & German Competence Network Sepsis (Sepnet). (2008). Acute renal failure in patients with severe sepsis and septic shock—A significant independent risk factor for mortality: Results from the German Prevalence Study. Nephrology, Dialysis, Transplantation, 23(3), 904- 909

Palevsky, P. M. (2013). Renal replacement therapy in acute kidney injury. Advances in Chronic Kidney Disease, 20(1), 76-84

Prowle, J. R., & Davenport, A. (2015). Does early-start renal replacement therapy improve outcomes for patients with acute kidney injury? Kidney International, 88(4), 670-673

Ricci, Z., Cruz, D. N., & Ronco, C. (2011). Classification and staging of acute kidney injury: Beyond the RIFLE and AKIN criteria. Nature Reviews Nephrology, 7(4), 201-208

Schneider, A. G., & Bagshaw, S. M. (2014). Effects of renal replacement therapy on renal recovery after acute kidney injury. Nephron Clinical Practice, 127(1-4), 35-41

Schrier, R. W. (2010). ARF, AKI, or ATN? Nature Reviews Nephrology, 6(3), 125- 125

Schrier, R. W., & Wang, W. (2004). Acute renal failure and sepsis. The New England Journal of Medicine, 351(2), 159-169

Singh, T. B., Rathore, S. S., Choudhury, T. A., Shukla, V. K., Singh, D. K., & Prakash, J. (2013). Hospital-acquired acute kidney injury in medical, surgical, and intensive care unit: A comparative study. Indian Journal of Nephrology, 23(1), 24-29. The Kidney Disease Improving Global Outcomes (KDIGO) Working Group. (2012). Section 2: AKI Definition. Kidney International Supplements, 2(1), 19-36. Van Berendoncks, A. M., Elseviers, M. M., Lins, R. L., & SHARF Study Group. (2010). Outcome of acute kidney injury with different treatment options: Long-term follow-up. Clinical Journal of the American Society of Nephrology, 5(10), 1755-1762

Vincent, J. L., Moreno, R., Takala, J., Willatts, S., De Mendonça, A., Bruining, H., Reinhart, C. K., Suter, P. M., & Thijs, L. G. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Medicine, 22(7), 707-710

Descargas

Publicado

2021-09-15

Número

Sección

Artículos originales

Cómo citar

Injuria renal aguda en unidad de cuidados intensivos. (2021). Revista UniNorte De Medicina Y Ciencias De La Salud, 10(1), 125-136. https://doi.org/10.5281/zenodo.6884912

Artículos más leídos del mismo autor/a