Trend in mortality from chronic kidney disease in Brazil and its regions, 2013-2023: an ecological time-series study
DOI:
https://doi.org/10.5281/zenodo.22150016Keywords:
renal insufficiency, chronic, mortality, time series studies, healthcare disparities, Brazil, epidemiologyAbstract
Introduction: Chronic kidney disease affects more than 10% of the world population and its mortality has increased over the past two decades. In Brazil an upward trend with sociodemographic disparities has been described. The aim was to analyze the trend in mortality from chronic kidney disease in Brazil and its five macro-regions between 2013 and 2023, by sex and age group. Materials and methods: Ecological time-series study with deaths whose underlying cause was chronic kidney disease (ICD-10 code N18) from the Mortality Information System, and population denominators from the Brazilian Institute of Geography and Statistics. Rates per 100,000 inhabitants were calculated and the mean annual change was estimated by simple linear regression, with significance at p < 0.05. Results: 83,787 deaths were recorded; 57.5% were men and 32.9% were people aged 80 years or older. The national rate rose from about 3.5 to 4.0 per 100,000 inhabitants, with a mean annual increase of 0.090 per 100,000 (95% confidence interval: 0.053 to 0.126; p < 0.001). All five macro-regions showed a significant upward trend. Conclusions: In Brazil mortality from chronic kidney disease increased between 2013 and 2023, concentrated in men and older people and widespread across all regions. Because of its ecological design with aggregated data, the study describes the trend but does not allow establishment of its causes; the findings support strengthening detection in primary care and reducing regional inequalities in access to nephrological care.References
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Copyright (c) 2025 João Paulo de Morais Sonda, Juliana Barbosa Lima Ribeiro, Silvia Carolina Castro Sampaio, Ramón Mario Bellón Préstamo (Autor/a)
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