Recurrent acute lithiasic pancreatitis in the late puerperium without index cholecystectomy: a case report

Authors

  • Jucélia Aparecida Farias Pereira Carrera de Medicina, Facultad de la Universidad del Norte en Pedro Juan Caballero, Paraguay Autor/a
  • Zara Escobar Benítez Carrera de Medicina, Facultad de la Universidad del Norte en Pedro Juan Caballero, Paraguay Autor/a

DOI:

https://doi.org/10.5281/zenodo.21909571

Keywords:

acute pancreatitis, recurrence, cholelithiasis, cholecystectomy, postpartum period, case report

Abstract

Objective: To describe a case of recurrent acute lithiasic pancreatitis in the late puerperium, focusing on factors that delayed cholecystectomy.

Methods: We present the case of a 34-year-old woman from inland Paraguay, in late puerperium (2 months), with irregularly treated arterial hypertension, who had two episodes of right-upper-quadrant pain radiating to the back, with vomiting, 15 days apart.

Results: In the first episode, laboratory tests showed marked lipase and amylase elevation, elevated transaminases and total bilirubin of predominantly indirect type; abdominal ultrasound showed hepatic steatosis, multiple gallstones, a common bile duct dilated to 11 mm and free abdominal fluid. Acute lithiasic pancreatitis was diagnosed and managed with parenteral hydration and analgesia, without cholecystectomy during that admission. Fifteen days after discharge she was readmitted with similar symptoms; repeat ultrasound showed gallbladder wall thickening, pericholecystic fluid and confirmed cholelithiasis, with renewed amylase elevation. After confirmed recurrence, combined medical and surgical management was chosen and cholecystectomy was scheduled to address the underlying lithiasic cause.

Conclusion: This case illustrates how lack of cholecystectomy during the index admission for acute lithiasic pancreatitis, influenced by limited access to care inland, was associated with early disease recurrence, and underscores the importance of timely cholecystectomy to prevent recurrent biliary pancreatitis.

References

Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102-111. https://doi.org/10.1136/gutjnl-2012-302779

Kimura Y, Takada T, Kawarada Y, Hirata K, Mayumi T, Yoshida M, et al. JPN Guidelines for the management of acute pancreatitis: treatment of gallstone-induced acute pancreatitis. J Hepatobiliary Pancreat Surg. 2006;13(1):56-60. https://doi.org/10.1007/s00534-005-1052-6

Sun H, Warren J, Yip J, Ji Y, Hao S, Han W, et al. Factors Influencing Gallstone Formation: A Review of the Literature. Biomolecules. 2022;12(4):550. https://doi.org/10.3390/biom12040550

Wang HH, Portincasa P, Liu M, Tso P, Wang DQ. An Update on the Lithogenic Mechanisms of Cholecystokinin A Receptor (CCKAR), an Important Gallstone Gene for Lith13. Genes (Basel). 2020;11(12):1438. https://doi.org/10.3390/genes11121438

Tóth K, Márton Z, Csontos C, Márton S. Acute Pancreatitis in Pregnancy and the Early Postpartum Period: An Anaesthesiology and Critical Care Perspective. J Clin Med. 2026;15(8):2968. https://doi.org/10.3390/jcm15082968

Somogyi L, Martin SP, Venkatesan T, Ulrich CD 2nd. Recurrent acute pancreatitis: an algorithmic approach to identification and elimination of inciting factors. Gastroenterology. 2001;120(3):708-717. https://doi.org/10.1053/gast.2001.22333

Stimac D, Stimac T. Acute pancreatitis during pregnancy. Eur J Gastroenterol Hepatol. 2011;23(10):839-844. https://doi.org/10.1097/MEG.0b013e328349b199

Blundell JD, Gandy RC, Close JCT, Harvey LA. Time to interval cholecystectomy and associated outcomes in a population aged 50 and above with mild gallstone pancreatitis. Langenbecks Arch Surg. 2023;408(1). https://doi.org/10.1007/s00423-023-03098-7

Ruiz Rebollo ML. Recurrent acute biliary pancreatitis: A frequent and preventable condition potentially associated with morbidity and mortality. Rev Esp Enferm Dig. 2022;114. https://doi.org/10.17235/reed.2022.8563/2021

Barreiro Alonso E, Mancebo Mata A, Varela Trastoy P, Pipa Muñiz M, López Fernández E, Tojo González R, et al. Reingresos por pancreatitis aguda biliar edematosa en pacientes sin colecistectomía. Rev Esp Enferm Dig. 2016;108(8):473-478. https://doi.org/10.17235/reed.2016.4291/2016

Bejarano González N, Romaguera Monzonís A, García Borobia FJ, et al. Cómo afecta el retraso de la colecistectomía tras la pancreatitis aguda litiásica en la aparición de recidivas: consecuencias de la falta de recursos. Rev Esp Enferm Dig. 2016;108(3):117-122.

Rey Chaves CE, Diaz Amarís JP, Diaz Tarazona MA, Sarmiento L, Conde D, Alarcón I, et al. Timing of Cholecystectomy After Acute Biliary Severe Pancreatitis: A Systematic Review-Time for A Clinical Trial? JGH Open. 2026. https://doi.org/10.1002/jgh3.70368

Arif AA, Sasson S, Aboalfaraj N, Karimuddin AA, Galorport C, Monkewich GJ, et al. Determinants and outcomes of early cholecystectomy for mild gallstone pancreatitis in British Columbia, Canada. J Can Assoc Gastroenterol. 2026. https://doi.org/10.1093/jcag/gwag007

Dima AL, Manda AL, Davitoiu DV, Lutic CV, Voiculescu DI. Current Approach in Acute Biliary Pancreatitis - a Narrative Review. Maedica (Bucur). 2026;21(1):167. https://doi.org/10.26574/maedica.2026.21.1.167

Gad MM, Ayad Q, Elgamal MM, Moubarak ES, Ziada AF, Beddor A, et al. Cholecystectomy versus conservative management for patients with uncomplicated symptomatic gallstones and cholecystitis: an updated systematic review and meta-analysis. BMC Surg. 2026. https://doi.org/10.1186/s12893-026-03922-z

Published

2024-06-19

Issue

Section

Case Reports

How to Cite

Recurrent acute lithiasic pancreatitis in the late puerperium without index cholecystectomy: a case report. (2024). Revista UniNorte De Medicina Y Ciencias De La Salud, 13(2), 56–59. https://doi.org/10.5281/zenodo.21909571

Most read articles by the same author(s)

Similar Articles

21-30 of 52

You may also start an advanced similarity search for this article.