Frequency of urinary tract infection and associated preterm birth among pregnant women aged 15 to 35 years attended at the Inmaculada Concepción District Hospital of Caaguazú, Paraguay

Authors

  • Kelli Fernanda Karnikowaki Universidad Central del Paraguay, Ciudad del Este, Paraguay Autor/a
  • Leonardo da Silva Ribas Universidad Central del Paraguay, Ciudad del Este, Paraguay Autor/a
  • Thauany Ferreira dos Santos Universidad Central del Paraguay, Ciudad del Este, Paraguay Autor/a
  • Ramón Bellón Préstamo Universidad Central del Paraguay, Ciudad del Este, Paraguay Autor/a

DOI:

https://doi.org/10.5281/zenodo.22165168

Keywords:

urinary tract infections, bacteriuria, pregnancy, premature birth, prenatal care, Paraguay

Abstract

Introduction: Urinary tract infection is one of the most frequent pregnancy complications and is associated with pyelonephritis and preterm birth. Local data from district hospitals in Paraguay are scarce. The aim was to describe the frequency of urinary tract infection among pregnant women aged 15 to 35 years attended in obstetrics at the Inmaculada Concepción District Hospital of Caaguazú, its clinical forms and characteristics, and the frequency of preterm birth among those affected, between January and June 2025. Materials and methods: Retrospective descriptive observational study based on medical record review. Cases were pregnant women with a clinical or laboratory diagnosis of urinary tract infection. Analysis was descriptive. Results: Of 617 pregnant women attended, 75 had at least one episode (12.2%). Stable union (73.3%), secondary schooling (68.0%), nulliparity (49.3%) and incomplete antenatal care (73.3%) predominated. The most frequent form was asymptomatic bacteriuria (60.3%), followed by cystitis (37.0%); there were 2 cases of pyelonephritis. Nine women (12.0%) had preterm birth, mostly moderate. Conclusions: Infection affected about 1 in 8 pregnant women attended, mainly as asymptomatic bacteriuria and with incomplete antenatal care; preterm birth was the most frequent perinatal complication. The findings support urine culture screening from the first trimester and strengthening antenatal care.

References

Ansaldi Y, Martinez de Tejada Weber B. Urinary tract infections in pregnancy. Clin Microbiol Infect. 2023;29(10):1249-53. https://doi.org/10.1016/j.cmi.2022.08.015

Glaser AP, Schaeffer AJ. Urinary tract infection and bacteriuria in pregnancy. Urol Clin North Am. 2015;42(4):547-60. https://doi.org/10.1016/j.ucl.2015.05.004

Matuszkiewicz-Rowińska J, Małyszko J, Wieliczko M. Urinary tract infections in pregnancy: old and new unresolved diagnostic and therapeutic problems. Arch Med Sci. 2015;11(1):67-77. https://doi.org/10.5114/aoms.2013.39202

de Souza HD, Diório GRM, Peres SV, Francisco RPV, Galletta MAK. Bacterial profile and prevalence of urinary tract infections in pregnant women in Latin America: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2023;23(1):774. https://doi.org/10.1186/s12884-023-06060-z

Fretes MS, Fretes NE, Villagra AR, Galeano A, Oviedo RV, Santa Cruz FV. Infección urinaria en embarazadas que asisten al consultorio externo del Hospital Materno Infantil Santísima Trinidad. Asunción, Paraguay. An Fac Cienc Med (Asunción). 2020;53(1):31-40. Disponible en: http://scielo.iics.una.py/scielo.php?script=sci_arttext&pid=S1816-89492020000100031

Nicolle LE, Gupta K, Bradley SF, Colgan R, DeMuri GP, Drekonja D, et al. Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America. Clin Infect Dis. 2019;68(10):1611-5. https://doi.org/10.1093/cid/ciz021

US Preventive Services Task Force; Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, et al. Screening for asymptomatic bacteriuria in adults: US Preventive Services Task Force recommendation statement. JAMA. 2019;322(12):1188-94. https://doi.org/10.1001/jama.2019.13069

Smaill FM, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2019;(11):CD000490. https://doi.org/10.1002/14651858.CD000490.pub4

Ohuma EO, Moller AB, Bradley E, Chakwera S, Hussain-Alkhateeb L, Lewin A, et al. National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis. Lancet. 2023;402(10409):1261-71. https://doi.org/10.1016/S0140-6736(23)00878-4

Walani SR. Global burden of preterm birth. Int J Gynaecol Obstet. 2020;150(1):31-3. https://doi.org/10.1002/ijgo.13195

Chawanpaiboon S, Vogel JP, Moller AB, Lumbiganon P, Petzold M, Hogan D, et al. Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. Lancet Glob Health. 2019;7(1):e37-46. https://doi.org/10.1016/S2214-109X(18)30451-0

Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371(9606):75-84. https://doi.org/10.1016/S0140-6736(08)60074-4

Romero R, Dey SK, Fisher SJ. Preterm labor: one syndrome, many causes. Science. 2014;345(6198):760-5. https://doi.org/10.1126/science.1251816

Farkash E, Weintraub AY, Sergienko R, Wiznitzer A, Zlotnik A, Sheiner E. Acute antepartum pyelonephritis in pregnancy: a critical analysis of risk factors and outcomes. Eur J Obstet Gynecol Reprod Biol. 2012;162(1):24-7. https://doi.org/10.1016/j.ejogrb.2012.01.024

Wing DA, Fassett MJ, Getahun D. Acute pyelonephritis in pregnancy: an 18-year retrospective analysis. Am J Obstet Gynecol. 2014;210(3):219.e1-6. https://doi.org/10.1016/j.ajog.2013.10.006

Schneeberger C, Kazemier BM, Geerlings SE. Asymptomatic bacteriuria and urinary tract infections in special patient groups: women with diabetes mellitus and pregnant women. Curr Opin Infect Dis. 2014;27(1):108-14. https://doi.org/10.1097/QCO.0000000000000028

Kazemier BM, Koningstein FN, Schneeberger C, Ott A, Bossuyt PM, de Miranda E, et al. Maternal and neonatal consequences of treated and untreated asymptomatic bacteriuria in pregnancy: a prospective cohort study with an embedded randomised controlled trial. Lancet Infect Dis. 2015;15(11):1324-33. https://doi.org/10.1016/S1473-3099(15)00070-5

Abde M, Weis N, Kjærbye-Thygesen A, Moseholm E. Association between asymptomatic bacteriuria in pregnancy and adverse pregnancy- and birth outcomes. A systematic review. Eur J Obstet Gynecol Reprod Biol. 2024;302:116-24. https://doi.org/10.1016/j.ejogrb.2024.09.001

Wingert A, Pillay J, Sebastianski M, Gates M, Featherstone R, Shave K, et al. Asymptomatic bacteriuria in pregnancy: systematic reviews of screening and treatment effectiveness and patient preferences. BMJ Open. 2019;9(3):e021347. https://doi.org/10.1136/bmjopen-2017-021347

González AS, Díaz GD, Penayo C, Jara RR. Prevalencia de infección de las vías urinarias en mujeres embarazadas de 18 a 30 años que acuden al Hospital Distrital Inmaculada Concepción de Caaguazú en el periodo de enero a noviembre de 2022. Rev Cient Estud FCS-USCA (MOMA). 2022;3(2):27-32.

Published

2026-08-29

Issue

Section

Original Articles

How to Cite

Frequency of urinary tract infection and associated preterm birth among pregnant women aged 15 to 35 years attended at the Inmaculada Concepción District Hospital of Caaguazú, Paraguay. (2026). Revista UniNorte De Medicina Y Ciencias De La Salud, 15(2), 91–96. https://doi.org/10.5281/zenodo.22165168

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